Views: 0 Author: Site Editor Publish Time: 2026-03-12 Origin: Site
The core mechanism of plant extraction using ultrasonic homogenizers is the "acoustic cavitation effect." This physical process differs from traditional extraction methods that rely on chemical penetration or simple mechanical disruption. It achieves efficient cell wall disruption and rapid release of active ingredients without depending on high temperatures, high pressures, or harmful chemical reagents. The process can be divided into three stages: First, the equipment transmits high-frequency ultrasound (typically 20kHz to 100MHz) into the extraction system, creating alternating high-pressure and low-pressure cycles in the liquid medium. During the low-pressure cycle, tiny vacuum bubbles form in the liquid. During the high-pressure cycle, these bubbles are rapidly compressed, eventually collapsing violently and generating strong shear forces and high-speed liquid microjets.
The mechanical force generated by this bubble collapse acts like countless miniature hammers, precisely and efficiently disrupting the plant's tough cell walls and membranes, breaking down the cell barriers that solvents struggle to penetrate in traditional extraction methods. Simultaneously, high-speed microjets enhance macroscopic turbulence and microscopic mixing in the liquid medium, significantly increasing the contact area between the extraction solvent and the active ingredients within plant cells. This accelerates the dissolution and mass transfer of target bioactive molecules such as flavonoids, polyphenols, and polysaccharides, fundamentally improving extraction efficiency and yield. It is noteworthy that this process relies solely on physical processes, without involving thermal energy or chemical reactions, thus preserving the original structure and efficacy of the active ingredients to the greatest extent possible.
Most active ingredients in plants are encased within their cell walls, which traditional extraction methods struggle to completely destroy. This results in a significant amount of active ingredients remaining unextracted, leading to a waste of plant resources. Ultrasonic homogenizers, through intense shearing force and microjets, can thoroughly break down plant cell walls and even disrupt the internal microstructure of cells, allowing the solvent to fully penetrate and maximize the dissolution and separation of active ingredients. Studies have shown that ultrasonic homogenization extraction increases the extraction rate by 30%-50% compared to traditional methods. For some valuable medicinal plants (such as ginseng, dendrobium, and sea buckthorn), it allows for full utilization of raw materials, improving resource efficiency and reducing production costs. For example, using ultrasound-assisted eutectic solvent extraction to extract phenolic substances from sea buckthorn seed meal, the polyphenol yield is 1.6 times that of thermal reflux extraction under the same extraction time.
Compared to traditional solvent extraction, ultrasonic homogenization extraction requires no high temperature, takes less time, and has a higher extraction rate, while avoiding damage to active ingredients and solvent residue. Compared to enzyme-assisted extraction, it eliminates the need for expensive enzyme preparations, making the operation simpler and lower in cost, and it can thoroughly disrupt cell walls, avoiding the problem of incomplete enzymatic hydrolysis. Compared to supercritical fluid extraction, ultrasonic homogenization equipment has lower investment costs and is easier to operate, requiring no high-pressure equipment, making it suitable for large-scale production by small and medium-sized enterprises. It also has good extraction effects on both polar and non-polar active ingredients, overcoming the limitation of supercritical fluid extraction, which is only applicable to non-polar ingredients. In addition, ultrasonic homogenization can be combined with other extraction techniques (such as ultrasonic combined with Soxhlet extraction, ultrasonic combined with homogenization extraction) to further improve extraction efficiency. For example, ultrasonic combined with Soxhlet extraction can reduce the traditional Soxhlet extraction time by half without affecting the quality of the extract.