The dispersion and deagglomeration of solids in liquids is an important application of ultrasound systems. Ultrasonic cavitation generates high shear forces that break down particle agglomerates into individual dispersed particles. Mixing powders with liquids is a common step for a variety of products, such as paints, inks, shampoos, beverages or polishing media. Individual particles are held together by gravitational forces of various physical and chemical properties, including van der Waals forces and surface tension of liquids.

A wide variety of intermediates and consumer products such as cosmetics and skin care lotions, pharmaceutical ointments, varnishes, paints, lubricants and fuels are complete or partial emulsions. An emulsion is a dispersion of two or more immiscible liquids. High-intensity ultrasound provides the power needed to disperse the liquid phase (dispersed phase) into small droplets in the second stage (continuous phase). In the dispersion zone, the implosion of the cavitation bubble causes a strong shock wave, thus forming a high-velocity water jet. At appropriate energy density levels, ultrasound can well achieve average droplet sizes less than 1 micron (microemulsions).

Ultrasonic extraction of enzymes and proteins from cellular and subcellular particles is very effective as it significantly improves the ability of solvents to lift organic matter contained within the plant or seed body. Ultrasound has potential benefits in extracting and isolating new potential bioactive components, for example, extracting unused by-products formed in current processes.